Reproduction management

Pharmaceutical uses

eCG is the active pharmaceutical ingredient (API) in various veterinary drugs marketed in USA, most EU member states and other countries for use in e.g. cattle, goats, sheep, pigs, rabbits and/or deer. In veterinary medicine it is recommended for the stimulation of ovarian function and activity, improvement of fertility in estrus-synchronized animals and the induction of superovulation.

Value of eCG in farming

Drugs containing eCG allow farmers to:

Decrease workload by gaining more control over reproduction of their livestock.

Increase the fertility and thereby productivity of their animals.

Drive genetic diversity and select for certain traits by being able to count on successful artificial insemination.

These values have multiple positive effects, which can roughly be categorized into three categories. Those are:

Support of rural communities.
Biosecurity of farms.
Positive environmental impact.

How does eCG support rural communities?

More even reproductive activity throughout the year results in more balance between demand and supply of animal products, preventing a seasonal supply surplus with reduced product prices and spoilage, and a corresponding seasonal lack of products.

This makes the farming industry more profitable and convenient, so it can continue its role as the foundation of many rural communities.

How does eCG improve biosecurity of farms?

Successful artificial insemination decreases the need to transfer animals between farms and thereby minimizes the risk of entry of diseases.

Successful artificial insemination also allows farmers to select animals that are more resilient against diseases, decreasing the need for drugs and other treatments.

Age group uniformity reduces internal conflict and injury leading to less need for antibiotic treatments thereby decreasing the risk of antibiotic resistance.

How does eCG positively impact the environment?

With even reproductive activity throughout the year, products are continuously available locally, diminishing the need of product import.

Successful artificial insemination allows farmers to select for animals that use resources more efficiently.

It is known that in certain types of agriculture the use of eCG allows farmers to use 15% fewer animals, yet retaining the same productivity. This results in less use of resources, such as workforce, energy, housing, facilities, water, and fodder.

Assuming common portion sizes and general usage of eCG, Ísteka's eCG production has been estimated to save around 1 million tons of fodder each year.

Since fodder production has a large carbon footprint, this is very beneficial for the environment. The positive effects only increase after taking the diminished need for all other resources into the account as well.

Additionally, eCG can be beneficial for wildlife conservation since it has been shown to be useful before artificial insemination of a number of wild animals, mainly various ungulates and felids, but also other species such as collared peccaries, african clawed frogs, and squirrel monkeys.

Artificial biologics

Various research has been conducted to develop bioactive compounds with the same efficacy as natural eCG.

The development of these drugs is still at the experimental stage and none of them has been commercially approved in the Western world.